FCCH Project
FCCmigex DATABASE
A systematic evidence map to explore migrating and extractable food contact chemicals
The novel Database on Migrating and Extractable Food Contact Chemicals (FCCmigex) systematically maps the scientific evidence of food contact chemicals (FCCs) that have been measured in migrates and extracts of food contact materials and articles. It was compiled by a team of researchers from the Food Packaging Forum together with colleagues from eight academic institutions. The scientists analyzed 1,355 scientific studies that resulted from a systematic literature search and passed a two-phase screening process. In total, the database contains more than 4,000 food contact chemicals and over 24,000 database entries.
All FCCs in the database were investigated either for their presence in food contact materials, or for their propensity to transfer into food under real-world conditions, thus making human exposure to these chemicals highly probable. Importantly, only one third of FCCs that were detected in these studies were previously known to be used in the manufacture of food contact materials. And of all the materials investigated, 62% of the studies were on plastics with 3,239 different chemicals detected.The FCCmigex database is a product of the ongoing Food Contact Chemicals and Human Health (FCCH) Project led by the Food Packaging Forum. A peer-reviewed, open-access in the scientific journal Critical Reviews in Food Science and Nutrition provides detailed information about the compilation of the database and summarizes some of the key information. All data are accessible via the interactive tool below.
Getting started: Select from the home screen below to either explore (i) chemical data or (ii) reference data. The tool can be expanded into full-screen mode by clicking the double sided arrow in the bottom right corner. Check out the video on the right for a quick introduction on how to search the tool and find the data you’re most interested in.
The interactive tool above allows you to search and filter the data on food contact chemicals (FCCs) that have been measured in the migrates and extracts of many different food contact materials (FCMs) and articles (FCAs). There are two separate views within the tool: (1) the data view and (2) the references view.
In the data view, you are shown aggregated information on an almost countless number of questions related to FCCs, FCMs, FCAs, and beyond. Here are a few examples of possible questions that are answered by selecting the appropriate filters in the tool:
The reference view shows you which published studies are the source of the data. In the reference view, you can apply the same search and selection criteria as in the data view. There is also the option to search for authors and title keywords. The list of references shown summarizes all relevant sources that provide information about the filtered criteria. Example questions you can answer in this view are:
For some investigated food contact chemicals, we could not assign a CAS number during the screening process. In the interactive tool, we have only included food contact chemicals where a CAS number could be identified or for those FCCs that are mineral oil hydrocarbons, paraffins, or a few other common mixtures. As a consequence, the total number of database entries and references is lower in the interactive tool than the reported total numbers in the published in the journal Critical Reviews in Food Science. Please contact the Food Packaging Forum if you are interested in information on FCCs without CAS numbers.
In the future, we may still make small edits to the underlying data of the interactive tool to improve consistency which might lead to minor changes in absolute numbers.No, the FCCmigex database does not include any information on the concentrations of FCCs that were measured in migrates and extracts. However, the reference view of the tool above allows you to find the original scientific references for all database entries where you can extract this information.
In all works that reference the FCCmigex database, please cite both the Critical Reviews in Food Science and Nutrition journal article as well as this website:
Geueke B, Groh KJ, Maffini MV, Martin OV, Boucher JM, Chiang YT, Gwosdz F, Jieh P, Kassotis CD, Lanska P, Myers JP, Odermatt A, Parkinson LV, Schreier VN, Srebny V, Zimmermann L, Scheringer M and Muncke J (2022) “Systematic Evidence on migrating and extractable Food Contact Chemicals: Most Chemicals detected in Food Contact Materials are not listed for Use” Critical Reviews in Food Science and Nutrition, DOI: 10.1080/10408398.2022.2067828Food Packaging Forum Foundation (2022) “FCCmigex Database.” //topcookbox.com/fccmigexFor additional questions not answered here or in the , please send us an email: info@fp-forum.org. We will respond to you as soon as we are able.
For suggestions, we appreciate constructive feedback to help us improve the database and tool. Please fill out to share your thoughts with us.The work presented here is part of the Food Contact Chemicals and Human health (FCCH) Project. The FCCH project is funded by project-related grants from Sympany Foundation, MAVA Foundation, and Fondation Valery, as well as by the Food Packaging Forum’s (FPF) own resources from unrestricted donations.
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